"Whole Genome Sequencing is the future gold standard in DST. It is comprehensive, accessible, afforda"...read more
ΩTB® is a
Universal Drug
Resistance Test for TB
A single test for simultaneous evaluation of all resistance markers, as well as the differentiation between mixed infection, relapse and reinfection
TB and it’s global impact
India accounts for 2.7 million cases out of 10 million cases across the world.
- India 27%
- Rest 33%
- China 9%
- Indonesia 8%
- Philippines 6%
- Pakistan 6%
- Nigeria 4%
- Bangladesh 4%
- South Africa 3%
INDIA
27%
PAKISTAN
6%
CHINA
9%
NIGERIA
4%
BANGLADESH
4%
INDONESIA
8%
PHILIPPINES
6%
SOUTH
AFRICA
AFRICA
3%
REST
33%
Comparing ΩTB® (Omega TB) with current tests
| Drug Analysis | Antibiotic Coverage | |
|---|---|---|
 | ΩTB® | 18 antibiotics including bedaquiline and delamanid |
 | Culture Test | 13 - 15 antibiotics |
 | CBNAAT | 1 - 2 antibiotics |
 | LPA | Targeted for first line or second line |
ΩTB® Assessment Profile
- Test 18 antibiotics
- Specificity: 99.8%
- Sensitivity: 85-98%
- Phylogenetic reconstruction
- Identify mixed infection and coinfections including NTM/MOTT
- Strain Information
Benefits of ΩTB®
Comprehensive
DR profile of 18 drugs, Mixed infections and Co-infections incl NTM
Validated
Tested and validated on >10,000 genomes and >1000 clinical samples
Accurate
High sensitivity and specificity comparable to molecular methods
Affordable
Test cost less than or comparable to culture testing
Testimonials
Dr. V. K. Jain
Advisory Board,HaystackAnalytics Pvt Ltd
Dr. Digambar Behera
Advisory Board,HaystackAnalytics Pvt Ltd
"Whole Genome Sequencing has the potential to be the game changer in the treatment of TB and can ensu"...read more
Dr. Rajendra Prasad
Advisory Board,HaystackAnalytics Pvt Ltd
"There are >18 drugs which are currently used in different combinations and resistance to any drug in"...read more
Dr. V. Anilkumar
Clinical professor & HOD Microbiology,Amruta Institute of Medical Sciences, Kochi
"Whole Genome Sequencing is the Swiss Army Knife for the diagnosis of TB and detecting mutations asso"...read more
Dr. Eema Chaudhary
Professor and Head of the Department, TB and Respiratory Diseases,Subharti Medical College, Meerut
"Suspect earlier, treat earlier with Whole Genome Sequencing. Whole Genome Sequencing is the key to t"...read more
Research Papers
Prediction of treatment outcomes for multidrug-resistant tuberculosis by whole-genome sequencing.
He G, Chen X, Chen J, Zhang W
Cost-effectiveness of molecular diagnostic assays for the therapy of severe sepsis and septic shock in the emergency department.
Zacharioudakis IM, Zervou FN, Shehadeh F, Mylonakis E
The Effect of Molecular Rapid Diagnostic Testing on Clinical Outcomes in Bloodstream Infections: A Systematic Review and Meta-analysis.
Timbrook TT, Morton JB, McConeghy KW, Caffrey AR, Mylonakis E, LaPlante KL
Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania.
Katale BZ, Mbelele PM, Lema NA, Campino S, Mshana SE, Rweyemamu MM, Phelan JE, Keyyu JD, Majigo M, Mbugi EV, Dockrell HM, Clark TG, Matee MI, Mpagama S
Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might Affect Drug Susceptibility.
Advani J, Verma R, Chatterjee O, et al
Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole Genome Sequencing. MSphere.
Chen X, He G, Lin S, Wang S, Sun F, Chen J, Zhanga W
Optimization of sepsis therapy based on patient-specific digital precision diagnostics using next generation sequencing(DigiSep-Trial)—study protocol for a randomized, controlled, interventional, open-label, multicenter trial.
Brenner T, Skarabis A, Stevens P, et al
Whole-genome sequencing of presumptive MDR-TB isolates from a tertiary healthcare setting in Mumbai.
Amrutraj Zade, Sanchi Shah, Nilma Hirani, Kiran Kondabagil, Ameeta Joshi, Anirvan Chatterjee
COVID-19 and global childhood tuberculosis notifications.
Sachin Atre, Anirvan Chatterjee, Maha Farhat
Development of a PNA–DiSc2 based portable absorbance platform for the detection of pathogen nucleic acids
Shailesh B. Lad, Shomdutta Roy, Jijo Easo George, Himadri Chakraborti, Saumitra Lalsare, Bikash Barik, Arushi Singh, Amrutraj Zade, Sachee Agrawal, Jayanthi Shastri, Anirvan Chatterjee, Kantimay Das Gupta, Debjani Paul and Kiran Kondabagil
Giant viral genomic signatures in the previously reported gut metagenomes of pre-school children in rural India
Anirvan Chatterjee and Kiran Kondabagil
Whole genome sequencing of clinical strains of Mycobacterium tuberculosis from Mumbai, India: A potential tool for determining drug-resistance and strain lineage
AnirvanChatterjee, Kayzad Nilgiriwala, Dhananjaya Saranath, Camilla Rodrigues, Nerges Mistry
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
Francesc Coll, Jody Phelan, Grant A. Hill-Cawthorne, Mridul B. Nair, Kim Mallard, Shahjahan Ali, Abdallah M. Abdallah, Saad Alghamdi, Mona Alsomali, Abdallah O. Ahmed, Stephanie Portelli, Yaa Oppong, Adriana Alves, Theolis Barbosa Bessa, Susana Campino, Maxine Caws, Anirvan Chatterjee, Amelia C. Crampin, Keertan Dheda, Nicholas Furnham, Judith R. Glynn, Louis Grandjean, Dang Minh Ha, Rumina Hasan, Taane G. Clark
Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples
Antonina A. Votintseva, Phelim Bradley, Louise Pankhurst, Carlos del Ojo Elias, Matthew Loose, Kayzad Nilgiriwala, Anirvan Chatterjee, E. Grace Smith, Nicolas Sanderson, Timothy M. Walker, Marcus R. Morgan, David H. Wyllie, A. Sarah Walker, Tim E. A. Peto, Derrick W. Crook, Zamin Iqbal
Edge Implementation with Intel® NUC Mini PCs for MDR, XDR and XXDR Tuberculosis Genome Informatics Pipeline
Dr. Anirvan Chatterjee, Dr. Ramanathan Sethuraman, Lakshminarasimhan Ranganathan
Complete Genome Sequence of a New Megavirus Family Member Isolated from an Inland Water Lake for the First Time in India
Anirvan Chatterjee, Farhan Ali, Disha Bange, Kiran Kondabagil
Genomic and metagenomic signatures of giant viruses are ubiquitous in water samples from sewage, inland lake, waste water treatment plant, and municipal water supply in Mumbai, India
Anirvan Chatterjee, Thomas Sicheritz-Pontén, Rajesh Yadav & Kiran Kondabagil
Mimivirus encodes a multifunctional primase with DNA/RNA polymerase, terminal transferase and translesion synthesis activities
Ankita Gupta, Shailesh B Lad, Pratibha P Ghodke, P I Pradeepkumar, Kiran Kondabagil